Watch the official "Big Changes Are Coming" clip from the ABC medical drama series Grey's Anatomy Season 18 Episode 20, created by Shonda Rhimes. It stars Ellen Pompeo, Chandra Wilson, James Pickens, Jr., Kevin McKidd, Caterina Scorsone, Camilla Luddington, Kelly McCreary, Kim Raver, Jake Borelli, Chris Carmack, Richard Flood, Anthony Hill and Scott Speedman.<br /><br />You can watch Grey's Anatomy Season 18 Thursdays on ABC!
